The domain within your query sequence starts at position 252 and ends at position 426; the E-value for the RPT_1 domain shown below is 1.7e-7.

DRPKSSEDIIQPKKEDRPKSSEDSVPSKKGDRPKSSEDSVQPKKEDRPKSSEDSVQSKEG
EVHKPLKDSIQSKETKVPKSPQDSIQSKEDKTHRPLKDSVQSKESEEPKSSHESIQSKED
KIHKPLKDSIPSKEGDIPKSPEDTIQSQEEITASEEDTIQSQEGNTIKSSEEDVQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.