The domain within your query sequence starts at position 2973 and ends at position 3150; the E-value for the RPT_1 domain shown below is 6.61e-9.

DAKAEMTGEHNANLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVGFPLKLTGKIDFL
NNYALFLSPRAQQASWQASTRFNQYKYNQNFSAINNEHNIEASIGMNGDANLDFLNIPLT
IPEINLPYTEFKTPLLKDFSIWEETGLKEFLKTTKQSFDLSVKAQYKKNSDKHSIVVP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.