The domain within your query sequence starts at position 317 and ends at position 578; the E-value for the RPT_1 domain shown below is 4.23e-5.

SMEDALSVSMPKETTFMAFSSITSSPITRTQDEQIAIDAESTHLTIIPGTKFVPTLAEAS
LFPTIEGQAYTQDTPTTDEPMLTLTSTKSPSTYNASESVLTSITIKSDYQFFTNETTWTS
KSGQNLLTSMNTTTIPTFTSNKTLTLPFQGNATNRDHSSMTTNVSPIEASTESKVTTSSD
ATTASYTTALFKPTSQWLSHFTSVSGITSIASQPESKLTTLLLKSNSMPTVATNEFPSIP
SEPVAPSVNTSTLTDIKPNFST

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.