The domain within your query sequence starts at position 399 and ends at position 490; the E-value for the RPT_1 domain shown below is 8.76e-11.

EAVSTEHWHQSPRHAHHDLGRESEEEVAVKYSHHVASHRPQGHNADREEDSLEEHMNEVP
GHHHHRASRGDDEDISTEFGHKAPSHRLQDQD

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.