The domain within your query sequence starts at position 404 and ends at position 476; the E-value for the RPT_1 domain shown below is 4.61e-10.

PCPSAGKQEDCLTLKSHKLLTRSCSGDPRCEHNTNLKPHKLLSRSYSSNLRMEELYGLKN
HKLLSKSYSSAPK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.