The domain within your query sequence starts at position 496 and ends at position 643; the E-value for the RPT_1 domain shown below is 1.49e-19.

AGPLGLPGQKGDAGPIGLMGAPGPKGEKGDSGRGPFIHGEKGEKGSLGPPGPPGRDGSKG
MRGEPGELGEPGLPGEVGMRGPQGPPGLPGPAGPVGAPGLRGERGERGPPGEKGERGLDG
FPGKPGETGEQGRPGPPGVAGLQGEKGD

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.