The domain within your query sequence starts at position 745 and ends at position 890; the E-value for the RPT_1 domain shown below is 9.31e-5.

SSDITLRPSSGLIGPGAHQVFLISTYPKGTSWRQHIFYLNFNFYPQYLKEVSMQSREEPL
DLKLDTHKSIYFKPTWVGCSSTSNFTFHNPSRLPLQFEWRVSQEHQKVLAVQPSKGTIHP
NENLTLTWIFSPLEEIKYLFRVGIWV

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.