The domain within your query sequence starts at position 108 and ends at position 195; the E-value for the RPT_2 domain shown below is 4.1e-6.

HSSDLQTHDESNGLKRTKRITEYGKISSCINTEHILTGEKLPDHNQCGKVLGYKQIPCQY
QKIHTGEKSYECAEFGKIFTQKSQLRVH

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.