The domain within your query sequence starts at position 1395 and ends at position 1466; the E-value for the RPT_2 domain shown below is 4.38e-6.

GSASSEKGRAKDREHSGSEKDNPDKRKSGAQPDKESTVDRLSEQGHFKTLSQSSKETRTS
EKHESVRGSSNK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.