The domain within your query sequence starts at position 1453 and ends at position 1555; the E-value for the RPT_2 domain shown below is 1.33e-7.

CQQPCKRLLICSHKCQEPCTGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCVWRCQH
YQCTKLCSEPCNRPPCYVPCTKLLACGHPCIGLCGEPCPKKCR

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.