The domain within your query sequence starts at position 1491 and ends at position 1551; the E-value for the RPT_2 domain shown below is 2.05e-7.

SQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDG
D

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.