The domain within your query sequence starts at position 212 and ends at position 294; the E-value for the RPT_2 domain shown below is 8.51e-6.

EWGKLHVAILEREKQLRSEFERLECLQRIVSKLQMEAGLCEEQLNQADALLQSDIRLLAS
GKVAQRAGEVERDLDKADGMIRL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.