The domain within your query sequence starts at position 258 and ends at position 345; the E-value for the RPT_2 domain shown below is 6.53e-5.

TPEGAGCTLSDDTPLESPAVPTATCPLTLESAEDVSPLVSGGGRVQNSPPVGRKSVPLTT
ASEAVEVTLSDSGGQEDLPAKGLSVRLE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.