The domain within your query sequence starts at position 2920 and ends at position 2967; the E-value for the RPT_2 domain shown below is 5.7e-19.

FGQTEGSFQSSNCGQQGTTSYQSSGFDQQRSGLHQSFPCSNHESTSQE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.