The domain within your query sequence starts at position 380 and ends at position 568; the E-value for the RPT_2 domain shown below is 2.58e-16.

DMAETFDQGAHHAFGQGGREGGRLVQGAGQGLSHAAKEAQQFGHGHGHGYYAAGQTWQEG
DKVIRPGVSQAGEEMEQFGQGVRHTIKQAEKEAEKVAHGVQNGVNQAQKEAEKVAHGVQN
GVNQAQKEAEKVAHGVQNGVNQAQKEAEKVAHGVQTGVNQAGKETQRVGQGVQTGFNQGQ
KEAEKVAHG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.