The domain within your query sequence starts at position 2901 and ends at position 2955; the E-value for the RPT_3 domain shown below is 9.03e-17.

GQCGPFSGQSSGHIQHGPCFGQTEGSFQSSNCGQQGTTSYQSSGFDQQRSGLHQS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.