The domain within your query sequence starts at position 404 and ends at position 474; the E-value for the RPT_3 domain shown below is 3.67e-5.

TPLSTDVPERDMGPSKEGSAPPEGDPAFSERHMAFPGGGSIPPEGNTTPHKGVMEPPERD
MSPSKDNMAPP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.