The domain within your query sequence starts at position 55 and ends at position 275; the E-value for the RPT_3 domain shown below is 1.77e-6.

TRYRLQELRIRCVARKFLYLWIRVTFGRVTPSRARIFHEQKILQKVFGEWREEWWVSQRE
WKLCVRADCHYRYYLYNLIFQNWKTFVHQQREMRKRFRIAEHHDTKQKMCQAWKSWLIYM
VSRRTKLHMKTTALEFRRQSVLCFWWSKWRWRLGQAHAEHALHAVAVKHRALSLQLQGWL
RWQEQLLISQRDRRKEATAVQHYQHWQKQRSLKAWLKYLQI

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.