The domain within your query sequence starts at position 1355 and ends at position 1502; the E-value for the RPT_5 domain shown below is 3.23e-5.

WIYEQDEMLSIGIEEVFDILPLYGVLRPYSSHQISFTFYGHCDIIARAKALCEVEGGPTY
EVLLKGEASLVNYSFDTKDINYGLQLFDHVTEREITLKNTGKVGFEFNVLSNYRSSQRNL
LPGVPLILPLSGFIQSNKEQVLKVYYLP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.