The domain within your query sequence starts at position 419 and ends at position 471; the E-value for the RPT_6 domain shown below is 4.17e-5.

QRASGSGHSSCCEQHGTNSSQSSGFKQHGHESGQSCCGQHGTASSQSSGYSQH

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.