The domain within your query sequence starts at position 108 and ends at position 179; the E-value for the S4 domain shown below is 6.84e-4.

RRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGG
GRPGRVKRKNAK

S4

S4 RNA-binding domain

• SMART accession number: SM00363
• Description: -
• Interpro abstract (IPR002942):

  The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterised, small proteins that may be involved in translation regulation [ (PUBMED:10093218) ]. The S4 domain probably mediates binding to RNA [ (PUBMED:9707415) ].

• GO function: RNA binding (GO:0003723)

There are 146383 S4 domains in 146322 proteins in SMART's nrdb database.

Cellular role (predicted cellular role)

Binding / catalysis: RNA-binding

Literature (relevant references for this domain)

Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.

• Aravind L, Koonin EV
• Novel predicted RNA-binding domains associated with the translation machinery.
• J Mol Evol. 1999; 48: 291-302

Two previously undetected domains were identified in a variety of RNA-binding proteins, particularly RNA-modifying enzymes, using methods for sequence profile analysis. A small domain consisting of 60-65 amino acid residues was detected in the ribosomal protein S4, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. Another novel domain, designated PUA domain, after PseudoUridine synthase and Archaeosine transglycosylase, was detected in archaeal and eukaryotic pseudouridine synthases, archaeal archaeosine synthases, a family of predicted ATPases that may be involved in RNA modification, a family of predicted archaeal and bacterial rRNA methylases. Additionally, the PUA domain was detected in a family of eukaryotic proteins that also contain a domain homologous to the translation initiation factor eIF1/SUI1; these proteins may comprise a novel type of translation factors. Unexpectedly, the PUA domain was detected also in bacterial and yeast glutamate kinases; this is compatible with the demonstrated role of these enzymes in the regulation of the expression of other genes. We propose that the S4 domain and the PUA domain bind RNA molecules with complex folded structures, adding to the growing collection of nucleic acid-binding domains associated with DNA and RNA modification enzymes. The evolution of the translation machinery components containing the S4, PUA, and SUI1 domains must have included several events of lateral gene transfer and gene loss as well as lineage-specific domain fusions.

• Markus MA, Gerstner RB, Draper DE, Torchia DA
• The solution structure of ribosomal protein S4 delta41 reveals two subdomains and a positively charged surface that may interact with RNA.
• EMBO J. 1998; 17: 4559-71

S4 is one of the first proteins to bind to 16S RNA during assembly of the prokaryotic ribosome. Residues 43-200 of S4 from Bacillus stearothermophilus (S4 Delta41) bind specifically to both 16S rRNA and to a pseudoknot within the alpha operon mRNA. As a first step toward understanding how S4 recognizes and organizes RNA, we have solved the structure of S4 Delta41 in solution by multidimensional heteronuclear nuclear magnetic resonance spectroscopy. The fold consists of two globular subdomains, one comprised of four helices and the other comprised of a five-stranded antiparallel beta-sheet and three helices. Although cross-linking studies suggest that residues between helices alpha2 and alpha3 are close to RNA, the concentration of positive charge along the crevice between the two subdomains suggests that this could be an RNA-binding site. In contrast to the L11 RNA-binding domain studied previously, S4 Delta41 shows no fast local motions, suggesting that it has less capacity for refolding to fit RNA. The independently determined crystal structure of S4 Delta41 shows similar features, although there is small rotation of the subdomains compared with the solution structure. The relative orientation of the subdomains in solution will be verified with further study.

Metabolism (metabolic pathways involving proteins which contain this domain)

% proteins involved	KEGG pathway ID	Description
32.37	map03010	Ribosome
28.94	map00400	Phenylalanine, tyrosine and tryptophan biosynthesis
28.87	map00970	Aminoacyl-tRNA biosynthesis
6.78	map00240	Pyrimidine metabolism
0.30	map00350	Tyrosine metabolism
0.30	map00450	Selenoamino acid metabolism
0.30	map00340	Histidine metabolism
0.30	map00380	Tryptophan metabolism
0.30	map00440	Aminophosphonate metabolism
0.30	map00626	Naphthalene and anthracene degradation
0.30	map00150	Androgen and estrogen metabolism
0.15	map00260	Glycine, serine and threonine metabolism
0.15	map00300	Lysine biosynthesis
0.08	map00770	Pantothenate and CoA biosynthesis
0.08	map00620	Pyruvate metabolism
0.08	map00630	Glyoxylate and dicarboxylate metabolism
0.08	map00020	Citrate cycle (TCA cycle)
0.08	map00480	Glutathione metabolism
0.08	map00710	Carbon fixation
0.08	map00550	Peptidoglycan biosynthesis
0.08	map00030	Pentose phosphate pathway

This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with S4 domain which could be assigned to a KEGG orthologous group, and not all proteins containing S4 domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

Structure (3D structures containing this domain)

3D Structures of S4 domains in PDB

PDB code	Title
1c05	SOLUTION STRUCTURE OF RIBOSOMAL PROTEIN S4 DELTA 41, REFINED WITH DIPOLAR COUPLINGS (MINIMIZED AVERAGE STRUCTURE)
1c06	SOLUTION STRUCTURE OF RIBOSOMAL PROTEIN S4 DELTA 41, REFINED WITH DIPOLAR COUPLINGS (ENSEMBLE OF 16 STRUCTURES)
1dm9	HEAT SHOCK PROTEIN 15 KD
1eg0	FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME
1fjg	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN
1fka	STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION
1h3e	Tyrosyl-tRNA synthetase from Thermus thermophilus complexed with wild-type tRNAtyr(GUA) and with ATP and tyrosinol
1h3f	Tyrosyl-tRNA synthetase from Thermus thermophilus complexed tyrosinol
1hnw	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH TETRACYCLINE
1hnx	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH PACTAMYCIN
1hnz	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH HYGROMYCIN B
1hr0	CRYSTAL STRUCTURE OF INITIATION FACTOR IF1 BOUND TO THE 30S RIBOSOMAL SUBUNIT
1i94	CRYSTAL STRUCTURES OF THE SMALL RIBOSOMAL SUBUNIT WITH TETRACYCLINE, EDEINE AND IF3
1i95	CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH EDEINE
1i96	CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH THE TRANSLATION INITIATION FACTOR IF3 (C-TERMINAL DOMAIN)
1i97	CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TETRACYCLINE
1ibk	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTIC PAROMOMYCIN
1ibl	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE AND WITH THE ANTIBIOTIC PAROMOMYCIN
1ibm	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE
1j5e	Structure of the Thermus thermophilus 30S Ribosomal Subunit
1jgo	The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGO, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY
1jgp	The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGP, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY
1jgq	The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGQ, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY
1jh3	Solution structure of tyrosyl-tRNA synthetase C-terminal domain.
1jii	Crystal structure of S. aureus TyrRS in complex with SB-219383
1jij	Crystal structure of S. aureus TyrRS in complex with SB-239629
1jik	Crystal structure of S. aureus TyrRS in complex with SB-243545
1jil	Crystal structure of S. aureus TyrRS in complex with SB284485
1ksk	STRUCTURE OF RSUA
1ksl	STRUCTURE OF RSUA
1ksv	STRUCTURE OF RSUA
1ml5	Structure of the E. coli ribosomal termination complex with release factor 2
1n32	Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position at the a site with paromomycin
1n33	Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer rna anticodon stem-loop mismatched at the second codon position at the a site with paromomycin
1n34	Structure of the Thermus thermophilus 30S ribosomal subunit in the presence of codon and crystallographically disordered near-cognate transfer rna anticodon stem-loop mismatched at the first codon position
1n36	Structure of the Thermus thermophilus 30S ribosomal subunit in the presence of crystallographically disordered codon and near-cognate transfer RNA anticodon stem-loop mismatched at the second codon position
1qd7	PARTIAL MODEL FOR 30S RIBOSOMAL SUBUNIT
1qyu	Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluD
1v9f	Crystal structure of catalytic domain of pseudouridine synthase RluD from Escherichia coli
1vio	Crystal structure of pseudouridylate synthase
1vvj	1VVJ
1vy4	1VY4
1vy5	1VY5
1vy6	1VY6
1vy7	1VY7
1xmo	Crystal Structure of mnm5U34t6A37-tRNALysUUU Complexed with AAG-mRNA in the Decoding Center
1xmq	Crystal Structure of t6A37-ASLLysUUU AAA-mRNA Bound to the Decoding Center
1xnq	Structure of an Inosine-Adenine Wobble Base Pair Complex in the Context of the Decoding Center
1xnr	Crystal Structure of an Inosine-Cytosine Wobble Base Pair in the Context of the Decoding Center
2cqj	Solution structure of the S4 domain of U3 small nucleolar ribonucleoprotein protein IMP3 homolog
2e5l	A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine- Dalgarno interaction
2f4v	30S ribosome + designer antibiotic
2hhh	Crystal structure of kasugamycin bound to the 30S ribosomal subunit
2ist	crystal structure of RluD from E. coli
2jan	TYROSYL-TRNA SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS IN UNLIGANDED STATE
2k6p	Solution Structure of hypothetical protein, HP1423
2ts1	STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
2uu9	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUG-codon in the A-site and paromomycin.
2uua	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUC-codon in the A-site and paromomycin.
2uub	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUU-codon in the A-site and paromomycin.
2uuc	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUA-codon in the A-site and paromomycin.
2uxb	Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA GGGU in the context of the Thermus thermophilus 30S subunit.
2uxc	Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA UCGU in the context of the Thermus thermophilus 30S subunit.
2uxd	Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA CGGG in the context of the Thermus thermophilus 30S subunit.
2vqe	Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U-G wobble pairing during decoding
2vqf	Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U-G wobble pairing during decoding
2ykr	30S ribosomal subunit with RsgA bound in the presence of GMPPNP
2zm6	Crystal structure of the Thermus thermophilus 30S ribosomal subunit
3bbu	The Hsp15 protein fitted into the low resolution Cryo-EM map of the 50S.nc-tRNA.Hsp15 complex
3dh3	Crystal Structure of RluF in complex with a 22 nucleotide RNA substrate
3hp7	Putative hemolysin from Streptococcus thermophilus.
3j6x	3J6X
3j6y	3J6Y
3j77	3J77
3j78	3J78
3j7a	3J7A
3j7p	3J7P
3j7r	3J7R
3j80	3J80
3j81	3J81
3j9w	3J9W
3j9y	3J9Y
3j9z	3J9Z
3ja1	3JA1
3jag	3JAG
3jah	3JAH
3jai	3JAI
3jaj	3JAJ
3jam	3JAM
3jan	3JAN
3jap	3JAP
3jaq	3JAQ
3jbn	3JBN
3jbo	3JBO
3jbp	3JBP
3jbu	3JBU
3jbv	3JBV
3jcd	3JCD
3jce	3JCE
3jcj	3JCJ
3jcn	3JCN
3kbg	Crystal structure of the 30S ribosomal protein S4e from Thermoplasma acidophilum. Northeast Structural Genomics Consortium Target TaR28.
3oto	Crystal Structure of the 30S ribosomal subunit from a KsgA mutant of Thermus thermophilus (HB8)
3t1h	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin
3t1y	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin
3ts1	STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
4a2i	Cryo-electron Microscopy Structure of the 30S Subunit in Complex with the YjeQ Biogenesis Factor
4adv	Structure of the E. coli methyltransferase KsgA bound to the E. coli 30S ribosomal subunit
4aqy	Structure of ribsome-apramycin complexes
4b3m	Crystal structure of the 30S ribosome in complex with compound 1
4b3r	Crystal structure of the 30S ribosome in complex with compound 30
4b3s	Crystal structure of the 30S ribosome in complex with compound 37
4b3t	Crystal structure of the 30S ribosome in complex with compound 39
4bts	4BTS
4d5l	4D5L
4d61	4D61
4dr1	Crystal structure of the apo 30S ribosomal subunit from Thermus thermophilus (HB8)
4dr2	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with multiple copies of paromomycin molecules bound
4dr3	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with streptomycin bound
4dr4	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, cognate transfer RNA anticodon stem-loop and multiple copies of paromomycin molecules bound
4dr5	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, crystallographically disordered cognate transfer RNA anticodon stem-loop and streptomycin bound
4dr6	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position and streptomycin bound
4dr7	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, crystallographically disordered near-cognate transfer RNA anticodon stem-loop mismatched at the second codon position, and streptomycin bound
4duy	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U13C
4duz	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U13C, bound with streptomycin
4dv0	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G
4dv1	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G, bound with streptomycin
4dv2	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, C912A
4dv3	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, C912A, bound with streptomycin
4dv4	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A914G
4dv5	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A914G, bound with streptomycin
4dv6	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G
4dv7	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G, bound with streptomycin
4gkj	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUG-codon in the A-site and paromomycin.
4gkk	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUA-codon in the A-site and paromomycin
4ji0	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4ji1	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4ji2	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4ji3	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4ji4	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4ji5	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4ji6	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4ji7	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4ji8	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
4jv5	Crystal structures of pseudouridinilated stop codons with ASLs
4jya	Crystal structures of pseudouridinilated stop codons with ASLs
4k0k	Crystal structure of the Thermus thermophilus 30S ribosomal subunit complexed with a serine-ASL and mRNA containing a stop codon
4khp	Structure of the Thermus thermophilus 30S ribosomal subunit in complex with de-6-MSA-pactamycin
4kvb	4KVB
4kzx	Rabbit 40S ribosomal subunit in complex with eIF1.
4kzy	Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
4kzz	Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A
4l47	4L47
4l71	4L71
4lab	Crystal structure of the catalytic domain of RluB
4lel	4LEL
4lf4	4LF4
4lf5	4LF5
4lf6	4LF6
4lf7	4LF7
4lf8	4LF8
4lf9	4LF9
4lfa	4LFA
4lfb	4LFB
4lfc	4LFC
4lfz	4LFZ
4lgt	Crystal structure of the catalytic domain of RluB in complex with a 21-nucleotide RNA substrate
4lnt	4LNT
4lsk	4LSK
4lt8	4LT8
4nxm	Crystal Structure of the 30S ribosomal subunit from a GidB (RsmG) mutant of Thermus thermophilus (HB8)
4nxn	Crystal Structure of the 30S ribosomal subunit from a GidB (RsmG) mutant of Thermus thermophilus (HB8), bound with streptomycin
4oud	4OUD
4ox9	Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit
4p6f	4P6F
4p70	4P70
4tua	4TUA
4tub	4TUB
4tuc	4TUC
4tud	4TUD
4tue	4TUE
4u1u	4U1U
4u1v	4U1V
4u20	4U20
4u24	4U24
4u25	4U25
4u26	4U26
4u27	4U27
4u3m	4U3M
4u3n	4U3N
4u3u	4U3U
4u4n	4U4N
4u4o	4U4O
4u4q	4U4Q
4u4r	4U4R
4u4u	4U4U
4u4y	4U4Y
4u4z	4U4Z
4u50	4U50
4u51	4U51
4u52	4U52
4u53	4U53
4u55	4U55
4u56	4U56
4u6f	4U6F
4uer	4UER
4ug0	4UG0
4ujc	4UJC
4ujd	4UJD
4uje	4UJE
4v3p	4V3P
4v42	4V42
4v47	4V47
4v48	4V48
4v49	4V49
4v4a	4V4A
4v4b	4V4B
4v4g	4V4G
4v4h	4V4H
4v4i	4V4I
4v4j	4V4J
4v4n	4V4N
4v4p	4V4P
4v4q	4V4Q
4v4r	4V4R
4v4s	4V4S
4v4t	4V4T
4v4v	4V4V
4v4w	4V4W
4v4x	4V4X
4v4y	4V4Y
4v4z	4V4Z
4v50	4V50
4v51	4V51
4v52	4V52
4v53	4V53
4v54	4V54
4v55	4V55
4v56	4V56
4v57	4V57
4v5a	4V5A
4v5b	4V5B
4v5c	4V5C
4v5d	4V5D
4v5e	4V5E
4v5f	4V5F
4v5g	4V5G
4v5h	4V5H
4v5j	4V5J
4v5k	4V5K
4v5l	4V5L
4v5m	4V5M
4v5n	4V5N
4v5o	4V5O
4v5p	4V5P
4v5q	4V5Q
4v5r	4V5R
4v5s	4V5S
4v5y	4V5Y
4v5z	4V5Z
4v61	4V61
4v63	4V63
4v64	4V64
4v65	4V65
4v66	4V66
4v67	4V67
4v68	4V68
4v69	4V69
4v6a	4V6A
4v6c	4V6C
4v6d	4V6D
4v6e	4V6E
4v6f	4V6F
4v6g	4V6G
4v6i	4V6I
4v6k	4V6K
4v6l	4V6L
4v6m	4V6M
4v6n	4V6N
4v6o	4V6O
4v6p	4V6P
4v6q	4V6Q
4v6r	4V6R
4v6s	4V6S
4v6t	4V6T
4v6u	4V6U
4v6v	4V6V
4v6w	4V6W
4v6x	4V6X
4v6y	4V6Y
4v6z	4V6Z
4v70	4V70
4v71	4V71
4v72	4V72
4v73	4V73
4v74	4V74
4v75	4V75
4v76	4V76
4v77	4V77
4v78	4V78
4v79	4V79
4v7a	4V7A
4v7b	4V7B
4v7c	4V7C
4v7d	4V7D
4v7e	4V7E
4v7h	4V7H
4v7i	4V7I
4v7j	4V7J
4v7k	4V7K
4v7l	4V7L
4v7m	4V7M
4v7p	4V7P
4v7r	4V7R
4v7s	4V7S
4v7t	4V7T
4v7u	4V7U
4v7v	4V7V
4v7w	4V7W
4v7x	4V7X
4v7y	4V7Y
4v7z	4V7Z
4v83	4V83
4v84	4V84
4v85	4V85
4v87	4V87
4v88	4V88
4v89	4V89
4v8a	4V8A
4v8b	4V8B
4v8c	4V8C
4v8d	4V8D
4v8e	4V8E
4v8f	4V8F
4v8g	4V8G
4v8h	4V8H
4v8i	4V8I
4v8j	4V8J
4v8m	4V8M
4v8n	4V8N
4v8o	4V8O
4v8q	4V8Q
4v8u	4V8U
4v8x	4V8X
4v8y	4V8Y
4v8z	4V8Z
4v90	4V90
4v92	4V92
4v95	4V95
4v97	4V97
4v9a	4V9A
4v9b	4V9B
4v9c	4V9C
4v9d	4V9D
4v9h	4V9H
4v9i	4V9I
4v9j	4V9J
4v9k	4V9K
4v9l	4V9L
4v9m	4V9M
4v9n	4V9N
4v9o	4V9O
4v9p	4V9P
4v9q	4V9Q
4v9r	4V9R
4v9s	4V9S
4w29	4W29
4w2e	4W2E
4w2f	4W2F
4w2g	4W2G
4w2h	4W2H
4w2i	4W2I
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4wpo	4WPO
4wq1	4WQ1
4wqf	4WQF
4wqr	4WQR
4wqu	4WQU
4wqy	4WQY
4wr6	4WR6
4wra	4WRA
4wro	4WRO
4wsd	4WSD
4wsm	4WSM
4wt1	4WT1
4wt8	4WT8
4wu1	4WU1
4www	4WWW
4wzd	4WZD
4wzo	4WZO
4x62	4X62
4x64	4X64
4x65	4X65
4x66	4X66
4xej	4XEJ
4y4o	4Y4O
4y4p	4Y4P
4ybb	4YBB
4yhh	4YHH
4ypb	4YPB
4yy3	4YY3
4yzv	4YZV
4z3s	4Z3S
4z8c	4Z8C
4zer	4ZER
4zsn	4ZSN
5a2q	5A2Q
5a9z	5A9Z
5aa0	5AA0
5afi	5AFI
5aj0	5AJ0
5br8	5BR8
5czp	5CZP
5d8b	5D8B
5dat	5DAT
5dc3	5DC3
5dfe	5DFE
5dox	5DOX
5doy	5DOY
5e7k	5E7K
5e81	5E81
5el4	5EL4
5el5	5EL5
5el6	5EL6
5el7	5EL7
5f8k	5F8K
5fci	5FCI
5fcj	5FCJ
5fdu	5FDU
5fdv	5FDV
5flx	5FLX
5hau	5HAU
5hcp	5HCP
5hcq	5HCQ
5hcr	5HCR
5hd1	5HD1
5i4l	5I4L
5ib7	5IB7
5ib8	5IB8
5ibb	5IBB
5imq	5IMQ
5imr	5IMR
5iqr	5IQR
5it7	5IT7
5it8	5IT8
5it9	5IT9
5iwa	5IWA
5j30	5J30
5j3c	5J3C
5j4b	5J4B
5j4c	5J4C
5j4d	5J4D
5j5b	5J5B
5j7l	5J7L
5j88	5J88
5j8a	5J8A
5j8b	5J8B
5j91	5J91
5jb3	5JB3
5jc9	5JC9
5jpq	5JPQ
5jte	5JTE
5ju8	5JU8
5juo	5JUO
5jup	5JUP
5jus	5JUS
5jut	5JUT
5juu	5JUU
5k0y	5K0Y
5kcr	5KCR
5kcs	5KCS
5kps	5KPS
5kpv	5KPV
5kpw	5KPW
5kpx	5KPX
5l3p	5L3P
5lmn	5LMN
5lmo	5LMO
5lmp	5LMP
5lmq	5LMQ
5lmr	5LMR
5lms	5LMS
5lmt	5LMT
5lmu	5LMU
5lmv	5LMV
5lyb	5LYB
5lza	5LZA
5lzb	5LZB
5lzc	5LZC
5lzd	5LZD
5lze	5LZE
5lzf	5LZF
5lzs	5LZS
5lzt	5LZT
5lzu	5LZU
5lzv	5LZV
5lzw	5LZW
5lzx	5LZX
5lzy	5LZY
5lzz	5LZZ
5tga	5TGA

Links (links to other resources describing this domain)

• PFAM: S4
• INTERPRO: IPR002942
• PROSITE: RIBOSOMAL_S4