The domain within your query sequence starts at position 223 and ends at position 344; the E-value for the d1e8xa3 domain shown below is 4e-33.

ESTEPIGCPIEIVEVPQGSNKNLASFCNKVKKIRESYHASDINSNSGKIWAITTAYPSRL
FADTKFRVKISIDNSAQLLLLMPHANYLVKDLIAEILLLCANEPLSPKEYLLSVCGSEEF
LQ

This is a SCOP domain - please see the SCOP entry of d1e8xa3 for further annotation