The domain within your query sequence starts at position 223 and ends at position 371; the E-value for the d1e8xa3 domain shown below is 2e-42.
ESTEPIGCPIEIVEVPQGSNKNLASFCNKVKKIRESYHASDINSNSGKIWAITTAYPSRL FADTKFRVKISIDNSAQLLLLMPHANYLVKDLIAEILLLCANEPLSPKEYLLSVCGSEEF LQMDHSLGGHKIFQKNKSVIQLHLQKNRD