The domain within your query sequence starts at position 18 and ends at position 142; the E-value for the SNc domain shown below is 1.56e-18.

TVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDGKDTPDEP
WAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKAQSRTGFQNARNKQRHRRKGC
GVRAT

SNc

Staphylococcal nuclease homologues

• SMART accession number: SM00318
• Description: -
• Interpro abstract (IPR016071):

  Staphylococcus aureus nuclease (SNase) homologues, previously thought to be restricted to bacteria and archaea, are also in eukaryotes. Staphylococcal nuclease has a multi-domain organisation [ (PUBMED:9003410) ]. The human cellular coactivator p100 contains four repeats, each of which is a SNase homologue. These repeats are unlikely to possess SNase-like activities as each lacks equivalent SNase catalytic residues, yet they may mediate p100's single-stranded DNA-binding function [ (PUBMED:9041650) ]. A variety of proteins including many that are still uncharacterised belong to this group.

  SNase domains have an OB-fold consisting of a closed or partly open beta-barrel with Greek key topology [ (PUBMED:8475069) ].

There are 17529 SNc domains in 12929 proteins in SMART's nrdb database.

Literature (relevant references for this domain)

Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.

• Ponting CP
• P100, a transcriptional coactivator, is a human homologue of staphylococcal nuclease.
• Protein Sci. 1997; 6: 459-63

Staphylococcus aureus nuclease (SNase) homologues, previously thought to be restricted to bacteria and archaea, are demonstrated by sequence analysis to be present also in eukaryotes. The human cellular coactivator p100 is shown to contain four repeats, each of which is a SNase homologue. Surprisingly, these repeats are unlikely to possess SNase-like activities as each lacks equivalent SNase catalytic residues, yet they may mediate p100's single-stranded DNA-binding function. Products of Corydalis sempervirens and Saccharomyces cerevisiae open reading frames are predicted to adopt the same fold and possess similar functions as SNase. Five additional hypothetical proteins of bacterial origin are also predicted to be active SNase-like nucleases, including one that appears to be C-terminally truncated in a manner analogous to an engineered active SNase variant. Conservation of Asp-19 and Asp-83 among these homologues suggests a re-evaluation of the roles of these residues in Ca(2+)-binding and/or catalysis.

Structure (3D structures containing this domain)

3D Structures of SNc domains in PDB

PDB code	Title
1a2t	STAPHYLOCOCCAL NUCLEASE, B-MERCAPTOETHANOL DISULFIDE TO V23C VARIANT
1a2u	STAPHYLOCOCCAL NUCLEASE, V23C VARIANT, COMPLEX WITH 1-N-BUTANE THIOL AND 3',5'-THYMIDINE DIPHOSPHATE
1a3t	STAPHYLOCOCCAL NUCLEASE, V23C VARIANT, COMPLEX WITH 2-FLUOROETHANE THIOL AND 3',5'-THYMIDINE DIPHOSPHATE
1a3u	STAPHYLOCOCCAL NUCLEASE, CYCLOHEXANE THIOL DISULFIDE TO V23C VARIANT
1a3v	STAPHYLOCOCCAL NUCLEASE, CYCLOPENTANE THIOL DISULFIDE TO V23C VARIANT
1aex	STAPHYLOCOCCAL NUCLEASE, METHANE THIOL DISULFIDE TO V23C VARIANT
1ena	CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING
1enc	CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING
1eqv	SIMPLIFICATION OF A PROTEIN LOOP IN STAPHYLOCOCCAL NUCLEASE
1ey0	STRUCTURE OF WILD-TYPE S. NUCLEASE AT 1.6 A RESOLUTION
1ey4	STRUCTURE OF S. NUCLEASE STABILIZING MUTANT S59A
1ey5	STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T33V
1ey6	STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T41I
1ey7	STRUCTURE OF S. NUCLEASE STABILIZING MUTANT S128A
1ey8	STRUCTURE OF S. NUCLEASE STABILIZING TRIPLE MUTANT P117G/H124L/S128A
1ey9	STRUCTURE OF S. NUCLEASE STABILIZING QUADRUPLE MUTANT T41I/P117G/H124L/S128A
1eya	STRUCTURE OF S. NUCLEASE STABILIZING QUINTUPLE MUTANT T33V/T41I/P117G/H124L/S128A
1eyc	STRUCTURE OF S. NUCLEASE STABILIZING QUINTUPLE MUTANT T41I/S59A/P117G/H124L/S128A
1eyd	STRUCTURE OF WILD-TYPE S. NUCLEASE AT 1.7 A RESOLUTION
1ez6	STRUCTURE OF S. NUCLEASE STABILIZING SEXTUPLE MUTANT T33V/T41I/S59A/P117G/H124L/S128A
1ez8	STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T33V
1f2m	SIMPLIFICATION OF A PROTEIN LOOP IN STAPHYLOCOCCAL NUCLEASE
1f2y	SIMPLIFICATION OF A PROTEIN LOOP IN STAPHYLOCOCCAL NUCLEASE
1f2z	SIMPLIFICATION OF A PROTEIN LOOP IN STAPHYLOCOCCAL NUCLEASE
1ihz	Structure of S. nuclease mutant quintuple mutant V23L/V66L/I72L/I92L/V99L
1ii3	Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L
1jok	Averaged structure for Staphylococcal nuclease-H124L in ternary complex with Ca2+ and thymidine-3',5'-bisphosphate
1joo	Averaged structure for unligated Staphylococcal nuclease-H124L
1joq	Ensemble structures for Staphylococcal nuclease-H124L in ternary complex with Ca2+ and thymidine-3',5'-bisphosphate
1jor	Ensemble structures for unligated Staphylococcal nuclease-H124L
1kaa	STRESS AND STRAIN IN STAPHYLOCOCCAL NUCLEASE
1kab	STRESS AND STRAIN IN STAPHYLOCOCCAL NUCLEASE
1kda	STABILIZATION OF A STRAINED PROTEIN LOOP CONFORMATION THROUGH PROTEIN ENGINEERING
1kdb	STABILIZATION OF A STRAINED PROTEIN LOOP CONFORMATION THROUGH PROTEIN ENGINEERING
1kdc	STABILIZATION OF A STRAINED PROTEIN LOOP CONFORMATION THROUGH PROTEIN ENGINEERING
1nsn	THE CRYSTAL STRUCTURE OF ANTIBODY N10-STAPHYLOCOCCAL NUCLEASE COMPLEX AT 2.9 ANGSTROMS RESOLUTION
1nuc	STAPHYLOCOCCAL NUCLEASE, V23C VARIANT
1rkn	Solution structure of 1-110 fragment of Staphylococcal Nuclease with G88W mutation
1snc	THE CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF STAPHYLOCOCCAL NUCLEASE, CA2+, AND THE INHIBITOR PD*TP, REFINED AT 1.65 ANGSTROMS
1snd	STAPHYLOCOCCAL NUCLEASE DIMER CONTAINING A DELETION OF RESIDUES 114-119 COMPLEXED WITH CALCIUM CHLORIDE AND THE COMPETITIVE INHIBITOR DEOXYTHYMIDINE-3',5'-DIPHOSPHATE
1snm	ACTIVE SITE MUTANT GLU-43 (RIGHT ARROW) ASP IN STAPHYLOCOCCAL NUCLEASE DISPLAYS NONLOCAL STRUCTURAL CHANGES
1sno	PROTEIN STABILITY IN STAPHYLOCOCCAL NUCLEASE
1snp	PROTEIN STABILITY IN STAPHYLOCOCCAL NUCLEASE
1snq	PROTEIN STABILITY IN STAPHYLOCOCCAL NUCLEASE
1sta	ACCOMMODATION OF INSERTION MUTATIONS ON THE SURFACE AND IN THE INTERIOR OF STAPHYLOCOCCAL NUCLEASE
1stb	ACCOMMODATION OF INSERTION MUTATIONS ON THE SURFACE AND IN THE INTERIOR OF STAPHYLOCOCCAL NUCLEASE
1stg	TWO DISTINCTLY DIFFERENT METAL BINDING MODES ARE SEEN IN X-RAY CRYSTAL STRUCTURES OF STAPHYLOCOCCAL NUCLEASE-COBALT(II)-NUCLEOTIDE COMPLEXES
1sth	TWO DISTINCTLY DIFFERENT METAL BINDING MODES ARE SEEN IN X-RAY CRYSTAL STRUCTURES OF STAPHYLOCOCCAL NUCLEASE-COBALT(II)-NUCLEOTIDE COMPLEXES
1stn	THE CRYSTAL STRUCTURE OF STAPHYLOCOCCAL NUCLEASE REFINED AT 1.7 ANGSTROMS RESOLUTION
1sty	THE ALPHA ANEURISM: A STRUCTURAL MOTIF REVEALED IN AN INSERTION MUTANT OF STAPHYLOCOCCAL NUCLEASE
1syb	TRANSFER OF A BETA-TURN STRUCTURE TO A NEW PROTEIN CONTEXT
1syc	ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE
1syd	ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE
1sye	ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE
1syf	ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE
1syg	ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE
1tqo	Cryogenic Crystal Structure of Staphylococcal Nuclease Variant truncated Delta+PHS I92E
1tr5	Room temperature structure of Staphylococcal nuclease variant truncated Delta+PHS I92E
1tt2	Cryogenic crystal structure of Staphylococcal nuclease variant truncated Delta+PHS I92K
1u9r	Crystal Structure of Staphylococcal Nuclease mutant V66E/P117G/H124L/S128A at Room Temperature
2enb	CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING
2exz	Crystal structure of Staphylococcal nuclease mutant T22C
2ey1	Crystal structure of Staphylococcal nuclease mutant T22V
2ey2	Crystal structure of Staphylococcal nuclease mutant T41C
2ey5	Crystal structure of Staphylococcal nuclease mutant T41S
2ey6	Crystal structure of Staphylococcal nuclease mutant T41V
2eyf	Crystal structure of Staphylococcal nuclease mutant T44V
2eyh	Crystal structure of Staphylococcal nuclease mutant T62S
2eyj	Crystal structure of Staphylococcal nuclease mutant T62V
2eyl	Crystal structure of Staphylococcal nuclease mutant T82S
2eym	Crystal structure of Staphylococcal nuclease mutant T120C
2eyo	Crystal structure of Staphylococcal nuclease mutant T120S
2eyp	Crystal structure of Staphylococcal nuclease mutant T120V
2f0d	Crystal structure of Staphylococcal nuclease mutant I92V
2f0e	Crystal structure of Staphylococcal nuclease mutant V23L
2f0f	Crystal structure of Staphylococcal nuclease mutant L25I
2f0g	Crystal structure of Staphylococcal nuclease mutant V66I
2f0h	Crystal structure of Staphylococcal nuclease mutant V66L
2f0i	Crystal structure of Staphylococcal nuclease mutant I72L
2f0j	Crystal structure of Staphylococcal nuclease mutant I72V
2f0k	Crystal structure of Staphylococcal nuclease mutant V23I/L25I
2f0l	Crystal structure of Staphylococcal nuclease mutant V23L/I72L
2f0m	Crystal structure of Staphylococcal nuclease mutant V23L/I72V
2f0n	Crystal structure of Staphylococcal nuclease mutant L25I/I72L
2f0o	Crystal structure of Staphylococcal nuclease mutant V66I/I72V
2f0p	Crystal structure of Staphylococcal nuclease mutant V66I/V99I
2f0q	Crystal structure of Staphylococcal nuclease mutant V66L/I92L
2f0s	Crystal structure of Staphylococcal nuclease mutant V66L/I92V
2f0t	Crystal structure of Staphylococcal nuclease mutant V66L/V99I
2f0u	Crystal structure of Staphylococcal nuclease mutant V23I/L25I/I72V
2f0v	Crystal structure of Staphylococcal nuclease mutant V23L/V66L/I72L
2f0w	Crystal structure of Staphylococcal nuclease mutant V23I/L25I/V66L/I72L
2f3v	Solution structure of 1-110 fragment of staphylococcal nuclease with V66W mutation
2f3w	solution structure of 1-110 fragment of staphylococcal nuclease in 2M TMAO
2khs	Solution structure of SNase121:SNase(111-143) complex
2kq3	Solution structure of SNase140
2lkv	Staphylococcal Nuclease PHS variant
2m00	Solution structure of staphylococcal nuclease E43S mutant in the presence of ssDNA and Cd2+
2nuc	STAPHLOCOCCAL NUCLEASE, ETHANE THIOL DISULFIDE TO V23C VARIANT
2oeo	Cryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92D
2of1	Cryogenic crystal structure of the Staphylococcal Nuclease variant truncated Delta+PHS I92W
2oxp	Crystal Structure of Staphylococcal Nuclease mutant V66D/P117G/H124L/S128A
2pqe	Solution structure of proline-free mutant of staphylococcal nuclease
2pw5	Crystal Structure of Staphylococcal nuclease variant V66Y/P117G/H124L/S128A at room temperature
2pw7	Crystal Structure of Staphylococcal nuclease variant V66Y/P117G/H124L/S128A at 100K
2pyk	Crystal structure of Staphylococcal nuclease variant V66Q/P117G/H124L/S128A at room temperature
2pzt	Crystal structure of Staphylococcal nuclease variant V66Q/P117G/H124L/S128A at 100 K
2pzu	Crystal structure of Staphylococcal nuclease variant V66N/P117G/H124L/S128A at cryogenic temperature
2pzw	Crystal structure of Staphylococcal nuclease variant V66N/P117G/H124L/S128A at room temperature
2qdb	Crystal structure of staphylococcal nuclease variant E75Q/D21N/T33V/T41I/S59A/P117G/S128A at 100 K
2rbm	Crystal structure of Staphylococcal nuclease variant Delta+PHS I72K at cryogenic temperature
2rdf	Crystal Structure of staphyloccocal nuclease VIAGAN/E75A variant at cryogenic temperature
2rks	Crystal structure of Staphylococcal nuclease variant PHS L38K at cryogenic temperature
2snm	IN A STAPHYLOCOCCAL NUCLEASE MUTANT THE SIDE-CHAIN OF A LYSINE REPLACING VALINE 66 IS FULLY BURIED IN THE HYDROPHOBIC CORE
2sns	STAPHYLOCOCCAL NUCLEASE. PROPOSED MECHANISM OF ACTION BASED ON STRUCTURE OF ENZYME-THYMIDINE 3(PRIME),5(PRIME)-BIPHOSPHATE-CALCIUM ION COMPLEX AT 1.5-ANGSTROMS RESOLUTION
2sob	SN-OB, OB-FOLD SUB-DOMAIN OF STAPHYLOCOCCAL NUCLEASE, NMR, 10 STRUCTURES
2wac	Extended Tudor domain of Drosophila Melanogaster Tudor-SN (p100)
3bdc	Crystal structure of Staphylococcal nuclease variant Delta+PHS at cryogenic temperature
3bdl	Crystal structure of a truncated human Tudor-SN
3c1e	Crystal structure of Staphylococcal nuclease variant Delta+PHS L125K at cryogenic temperature
3c1f	Crystal structure of Staphylococcal nuclease variant Delta+PHS V104K at cryogenic temperature
3d4d	Crystal structure of Staphylococcal nuclease variant Delta+PHS Y91E at cryogenic temperature
3d4w	Crystal structure of Staphylococcal nuclease variant Delta+PHS A109R at cryogenic temperature
3d6c	Crystal structure of Staphylococcal nuclease variant PHS L38E at cryogenic temperature
3d8g	Crystal structure of Staphylococcal nuclease variant Delta+PHS I72R at cryogenic temperature
3dhq	Crystal structure of Staphylococcal nuclease variant Delta+PHS A90R at cryogenic temperature
3dmu	Crystal structure of Staphylococcal nuclease variant PHS T62K at cryogenic temperature
3e5s	Crystal structure of Staphylococcal nuclease variant Delta+PHS L103K at cryogenic temperature
3eji	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36K at cryogenic temperature
3ero	Crystal structure of Staphylococcal nuclease variant Delta+PHS I72E at cryogenic temperature
3erq	Crystal structure of Staphylococcal nuclease variant L25K at cryogenic temperature
3evq	Crystal structure of Staphylococcal nuclease variant Delta+PHS L25E at cryogenic temperature
3h6m	Crystal structure of Staphylococcal nuclease variant Delta+PHS V104E at cryogenic temperature
3hej	Crystal structure of Staphylococcal nuclease variant Delta+PHS T62R at cryogenic temperature
3hzx	Crystal Structure of Staphylococcal nuclease variant D+PHS/V66K at pH 9 determined at 100 K
3itp	Crystal structure of Staphylococcal nuclease variant Delta+PHS F34K at cryogenic temperature
3lx0	Crystal structure of Staphylococcal nuclease variant Delta+PHS D21N at cryogenic temperature
3meh	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A at cryogenic temperature
3mhb	Crystal structure of Staphylococcal nuclease variant Delta+PHS L38A at cryogenic temperature
3mvv	Crystal structure of Staphylococcal nuclease variant Delta+PHS F34A at cryogenic temperature
3mxp	Crystal structure of Staphylococcal nuclease variant Delta+PHS T62A at cryogenic temperature
3mz5	Crystal structure of Staphylococcal nuclease variant Delta+PHS L103A at cryogenic temperature
3nhh	Crystal structure of Staphylococcal nuclease variant V23E-L36K at cryogenic temperature
3nk9	Crystal structure of Staphylococcal nuclease variant Delta+PHS V74A at cryogenic temperature
3np8	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36A at cryogenic temperature
3nqt	Crystal structure of Staphylococcal nuclease variant Delta+PHS V66A at cryogenic temperature
3nuc	STAPHLOCOCCAL NUCLEASE, 1-N-PROPANE THIOL DISULFIDE TO V23C VARIANT
3nxw	Crystal structure of Staphylococcal nuclease variant Delta+PHS L125A at cryogenic temperature
3oso	Crystal structure of Staphylococcal nuclease variant Delta+PHS L25A at cryogenic temperature
3owf	Crystal structure of Staphylococcal nuclease variant Delta+PHS V66R at cryogenic temperature
3p1h	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23K/I92A at cryogenic temperature
3p75	Crystal structure of Staphylococcal nuclease variant Delta+PHS V104D at cryogenic temperature
3pmf	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23A at cryogenic temperature
3qb3	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92KL25A at cryogenic temperature
3qoj	Cryogenic structure of Staphylococcal nuclease variant D+PHS/V23K
3qol	Crystal structure of Staphylococcal nuclease variant D+PHS/V23E at pH 6 determined at 100 K
3qon	Crystal structure of Staphylococcal nuclease variant D+PHS/V23K/L36E at pH 7 determined at 100 K
3r3o	Crystal structure of Staphylococcal nuclease variant Delta+PHS T62A at cryogenic temperature and with high redundancy
3ruz	Crystal structure of Staphylococcal nuclease variant Delta+PHS V74K at cryogenic temperature
3s9w	Crystal structure of Staphylococcal nuclease variant Delta+PHS M98G bound to Ca2+ and thymidine-5',3'-diphosphate at cryogenic temperature
3shl	Crystal structure of Staphylococcal nuclease variant Delta+PHS V74KL25A at cryogenic temperature
3sk4	Crystal structure of Staphylococcal nuclease variant Delta+PHS D21N/V23E at cryogenic temperature
3sk5	Crystal structure of Staphylococcal nuclease variant Delta+PHS V39D at cryogenic temperature
3sk6	Crystal structure of Staphylococcal nuclease variant Delta+NVIAGLA V23K/L36E at cryogenic temperature
3sk8	Crystal structure of Staphylococcal nuclease variant Delta+PHS M98G apo protein at cryogenic temperature
3sr1	Crystal structure of Staphylococcal nuclease variant Delta+PHS A69G bound to Ca2+ and thymidine-5',3'-diphosphate at cryogenic temperature
3sxh	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92AL103A at cryogenic temperature
3t13	Crystal structure of Staphylococcal nuclease variant Delta+PHS A69G at cryogenic temperature
3t16	Crystal structure of Staphylococcal nuclease variant NVIAGA/M98G at cryogenic temperature
3tme	Crystal structure of Staphylococcal nuclease variant Delta+NVIAGLA V23E at cryogenic temperature
3tp5	Crystal structure of Staphylococcal nuclease variant Delta+NVIAGLA V23E/L36E at cryogenic temperature
3tp6	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36E/L103K at cryogenic temperature
3tp7	Crystal structure of Staphylococcal nuclease variant Delta+PHS V99E at cryogenic temperature
3tp8	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36E at cryogenic temperature
3u9o	Crystal structure of Staphylococcal nuclease variant NVIAGA/N100G at cryogenic temperature
3v2t	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/V66A at cryogenic temperature
3va5	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/V23A at cryogenic temperature
4df7	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23L/V99I at cryogenic temperature
4dfa	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/L36A at cryogenic temperature
4dgz	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/L125A at cryogenic temperature
4du9	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/V74A at cryogenic temperature
4e6i	Crystal structure of Staphylococcal nuclease variant NVIAGA V99G at cryogenic temperature
4eqn	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23E/I72K at cryogenic temperature
4eqo	Crystal structure of Staphylococcal nuclease variant Delta+PHS V99D at cryogenic temperature
4eqp	Crystal structure of Staphylococcal nuclease variant Delta+PHS I72D at cryogenic temperature
4evo	Crystal structure of Staphylococcal nuclease variant NVIAGA/E122G at cryogenic temperature
4f7x	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/L25A at cryogenic temperature
4f8m	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23I/I92V at cryogenic temperature
4g57	Staphylococcal Nuclease double mutant I72L, I92L
4h7b	Crystal Structure of Staphylococcal nuclease mutant I72V/V99L
4hmi	Crystal structure of Staphylococcal nuclease variant Delta+PHS V99K at cryogenic temperature
4hmj	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36D at cryogenic temperature
4hth	Crystal structure of Staphylococcal nuclease variant Delta+VIAGLA at cryogenic temperature
4i65	Crystal Structure of Staphylococcal nuclease mutant V23I/L25V/I72V/I92V
4ial	Crystal structure of Staphylococcal nuclease variant Delta+PHS H121E at cryogenic temperature
4id6	Crystal Structure of Staphylococcal nuclease mutant V23I/I72L
4iun	Crystal structure of Staphylococcal nuclease variant Delta+PHS R126E at cryogenic temperature
4iz8	Crystal structure of Staphylococcal nuclease variant Delta+PHS H8E at cryogenic temperature
4j1m	Crystal structure of Staphylococcal nuclease variant Delta+PHS R105E at cryogenic temperature
4j6h	Crystal structure of Staphylococcal nuclease variant Delta+PHS H121Q at cryogenic temperature
4k14	Crystal Structure of Staphylococcal nuclease mutant V66I/V99L
4k2k	Crystal structure of Staphylococcal nuclease variant Delta+PHS L25A/L36A/I92A at cryogenic temperature
4k2l	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92Q at cryogenic temperature
4k5v	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23T/L36A/V99T at cryogenic temperature
4k5w	Crystal structure of Staphylococcal nuclease variant V23M/L25F/T62F at cryogenic temperature
4k5x	Crystal structure of Staphylococcal nuclease variant V23M/L36F at cryogenic temperature
4k6d	Crystal structure of Staphylococcal nuclease variant V23M/T62F at cryogenic temperature
4k8i	Crystal Structure of Staphylococcal Nuclease mutant I92V/V99L
4k8j	Crystal Structure of Staphylococcal nuclease mutant V23L/V66I
4kd3	Crystal structure of Staphylococcal nuclease variant Delta+PHS L25A/V66A/I92A at cryogenic temperature
4kd4	Crystal structure of Staphylococcal nuclease variant V23L/L25V/V66I/I72V at cryogenic temperature
4khv	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23S at cryogenic temperature
4kjn	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23T/V66A/V99T at cryogenic temperature
4kjo	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36A/V66T/V99T at cryogenic temperature
4kta	Crystal structure of Staphylococcal nuclease variant Delta+PHS R105Q at cryogenic temperatures
4kv6	Crystal structure of Staphylococcal nuclease variant Delta+PHS R126Q at cryogenic temperature
4ky5	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D at pH 7 and cryogenic temperature
4ky6	Crystal structure of Staphylococcal nuclease variant Delta+PHS L25D at pH 6 and cryogenic temperature
4ky7	Crystal structure of Staphylococcal nuclease variant Delta+PHS V74D at cryogenic temperature
4laa	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36H at cryogenic temperature
4me5	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23S/V66A at cryogenic temperature
4miu	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23T/V99T at cryogenic temperature
4n9p	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23T/L25A/V99T at cryogenic temperature
4n9t	Crystal structure of Staphylococcal nuclease variant Delta+PHS V66A/I92S at cryogenic temperature
4ndx	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92N at cryogenic temperature
4nkl	Crystal structure of Staphylococcal nuclease variant Delta+PHS V66A/I92Q at cryogenic temperature
4nmz	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23Q/V66A at cryogenic temperature
4np5	Crystal structure of Staphylococcal nuclease variant Delta+PHS V66A/I92N at cryogenic temperature
4odg	Crystal structure of Staphylococcal nuclease variant V23I/V66I/V74I/V99I at cryogenic temperature
4ol7	4OL7
4pmb	4PMB
4pmc	4PMC
4pny	Crystal structure of Staphylococcal nuclease variant Delta+PHS I72H at cryogenic temperature
4qb4	4QB4
4qf4	4QF4
4qmg	4QMG
4r8n	4R8N
4rkb	4RKB
4rkl	4RKL
4s3s	4S3S
4trd	4TRD
4wor	4WOR
4wrd	4WRD
4yij	4YIJ
4zq3	4ZQ3
4zui	4ZUI
4zuj	4ZUJ
5c3w	5C3W
5c3x	5C3X
5c4h	5C4H
5c4z	5C4Z
5c5l	5C5L
5c5m	5C5M
5c6a	5C6A
5cc4	5CC4
5cgk	5CGK
5cr3	5CR3
5cv4	5CV4
5cv5	5CV5
5cv6	5CV6
5cv7	5CV7
5cv8	5CV8
5cv9	5CV9
5dau	5DAU
5deh	5DEH
5e1f	5E1F
5e3f	5E3F
5egt	5EGT
5ekk	5EKK
5ekl	5EKL
5f2d	5F2D
5hgt	5HGT
5hur	5HUR
5i6w	5I6W
5i6y	5I6Y
5i9o	5I9O
5i9p	5I9P
5igb	5IGB
5igc	5IGC
5igd	5IGD
5ige	5IGE
5igf	5IGF
5igg	5IGG
5iif	5IIF
5ioc	5IOC
5iod	5IOD
5isr	5ISR
5j1z	5J1Z
5j22	5J22
5jav	5JAV
5job	5JOB
5k5p	5K5P
5kee	5KEE
5kgu	5KGU
5kix	5KIX
5kru	5KRU
5kyi	5KYI
5kyl	5KYL
5nuc	STAPHYLOCOCCAL NUCLEASE, 1-N-PENTANE THIOL DISULFIDE TO V23C VARIANT

Links (links to other resources describing this domain)

• INTERPRO: IPR016071
• PFAM: SNase