The domain within your query sequence starts at position 341 and ends at position 496; the E-value for the SNc domain shown below is 4.11e-59.



Staphylococcal nuclease homologues
SMART accession number:SM00318
Description: -
Interpro abstract (IPR016071):

Staphylococcus aureus nuclease (SNase) homologues, previously thought to be restricted to bacteria and archaea, are also in eukaryotes. Staphylococcal nuclease has a multi-domain organisation [ (PUBMED:9003410) ]. The human cellular coactivator p100 contains four repeats, each of which is a SNase homologue. These repeats are unlikely to possess SNase-like activities as each lacks equivalent SNase catalytic residues, yet they may mediate p100's single-stranded DNA-binding function [ (PUBMED:9041650) ]. A variety of proteins including many that are still uncharacterised belong to this group.

SNase domains have an OB-fold consisting of a closed or partly open beta-barrel with Greek key topology [ (PUBMED:8475069) ].

Family alignment:
View or

There are 17529 SNc domains in 12929 proteins in SMART's nrdb database.

Click on the following links for more information.