The domain within your query sequence starts at position 3 and ends at position 91; the E-value for the THAP domain shown below is 4.74e-21.



SMART accession number:SM00980
Description: The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes (PUBMED:12575992).
Family alignment:
View or

There are 14352 THAP domains in 12471 proteins in SMART's nrdb database.

Click on the following links for more information.