Domains within Bos taurus protein A6QPW6_BOVIN (A6QPW6)

SERPINI2 protein

Alternative representations: 1 /

Protein length405 aa
Source databaseUniProt
Identifiers A6QPW6, A6QPW6_BOVIN, ENSBTAP00000015176.5, ENSBTAP00000015176, F1MNR9
Source gene ENSBTAG00000011423

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A6QPW6_BOVIN is shown as SERPINI2 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SERPINI2

Protein A6QPW6_BOVIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04610Complement and coagulation cascades

KEGG orthologous groups

KONameDescription
K04525SERPINAserpin A

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9913.ENSBTAP00000015176 in eggNOG.

OGTaxonomic classDescription
LCOG4826All organisms (root)serpin A,serpin B,serpin peptidase inhibitor, clade H, member 1
KOG2392Eukaryota (superkingdom)serpin A,serpin B,serpin peptidase inhibitor, clade H, member 1
HTCWEMetazoa (kingdom)serpin A,serpin B,leukocyte elastase inhibitor
93ED2Chordata (phylum)serpin I2
5R4RGSarcopterygii (superclass)serpin I2
8Z6HSMammalia (class)serpin I2
BQNYSLaurasiatheria (superorder)serpin I2
AX4V9Artiodactyla (order)serpin I2
B675QPecora (infraorder)serpin I2
7HDH9Opisthokonta (clade)serpin A,serpin B,leukocyte elastase inhibitor
9GUH1Vertebrata (clade)serpin I2
H4UFABilateria (clade)serpin A,serpin B,leukocyte elastase inhibitor
7PG3DBovidae (family)serpin I2
DB0MKBovinae (subfamily)serpin I2
AZIMKBos (genus)serpin I2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: